This server provides access to the program GenomeScan for
predicting the locations and exon-intron structures of genes in
genomic sequences from a variety of organisms.
GenomeScan incorporates protein homology information when predicting
genes. This server allows you to input proteins suspected to be
similar to regions of your DNA sequence. You can find such proteins by
doing a BLASTX comparison of your sequence to all known proteins, or
by running GENSCAN and then comparing the results to known proteins
using BLASTP. Please input the proteins in FastA format; the file may
contain multiple proteins so long as each is separated by a header
on its own line. Files should contain less than one million bases.
If you would like to test the program, feel free to use this DNA testfile
and the corresponding protein file.
You may also wish to use or read about the GENSCAN server, GenomeScan's predecessor.
Sequence name (optional):
Predicted peptides only
Predicted CDS and peptides
Upload your DNA sequence file (one-letter code, upper or lower case,
Or paste your DNA sequence here (one-letter code, upper or lower case,
Upload protein(s) with similarity to genomic sequence (FastA format):
Or paste your protein(s) here (FastA format):
GenomeScan was developed by Chris Burge in the Biology Department at
MIT. The GenomeScan program and the model that underlies it are
Yeh, R.-F., Lim, L. P. and Burge, C. B. (2001) Computational inference
of homologous gene structures in the human genome. Genome Res.
GenomeScan is based in part on GENSCAN, described in:
Burge, C. and Karlin, S. (1997) Prediction of complete
gene structures in human genomic DNA.
J. Mol. Biol. 268, 78-94.
Burge, C. B. and Karlin, S. (1998) Finding the genes in genomic DNA.
Curr. Opin. Struct. Biol. 8, 346-354.
This web server is located in the Burge laboratory
at the MIT Department of Biology.
Copyright © 2001-2002 Christopher Burge
Address any comments/questions/suggestions about this page to Chris Burge: (firstname.lastname@example.org)