Christopher Burge Laboratory
 
 
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2007 2006 2005 2004 2003 2002 2001 Complete List  

2008

Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB. (2008). Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 320, 1643-7. ABSTRACT.   Download PDF

Wang Z, Burge CB. (2008). Splicing regulation: From a parts list of regulatory elements to an integrated splicing code.
RNA 14, 802-813.

Boyerinas B, Park S-M, Shomron N, Hedegaard MM, Vinther J, Andersen JS, Feig C, Xu J, Burge CB, Peter, ME. (2008). Identification of let-7 regulated oncofetal genes. Cancer Res. 68, 2587-2591.

2007

Xiao X., Wang Z., Jang M. and Burge CB. (2007). Coevolutionary Networks of Splicing cis-Regulatory Elements. PNAS 104, 18583-18588.

Nielsen CB, Shomron N, Sandberg R, Hornstein E, Burge C.B. (2007). Determinants of Targeting by Endogenous and Exogenous MicroRNAs and siRNAs. RNA 13, 1894-1910.

Giorgi C, Yeo GW, Stone ME, Katz DB, Burge C, Turrigiano G, Moore MJ. (2007). The EJC Factor eIF4AIII Modulates Synaptic Strength and Neuronal Protein Expression. Cell 130, 179-91.

Neilson, JR, Zheng, GXY., Burge, CB, Sharp, PA. (2007). Dynamic regulation of miRNA expression in ordered stages of cellular development.  Genes Dev. 21, 578-89.

Ruvinsky I, Ohler U, Burge CB, Ruvkun, G. (2007). Detection of broadly expressed neuronal genes in C. elegans. Dev. Biol. 302, 617-626.

Ibrahim EC, Hims MM, Shomron N, Burge CB, Slaugenhaupt SA, Reed R. (2007). Weak Definition of IKBKAP exon 20 leads to aberrant splicing in familial dysautonomia. Hum Mutat. 28, 41-53.

2006

Stadler M B, Shomron N, Yeo G, Schneider A, Xiao X, Burge CB. (2006). Inference of Splicing Regulatory Activities by Sequence Neighborhood Analysis. PLoS Genet. 2, e191.

Engels R, Yu T, Burge CB, Mesirov, JP, Decaprio, D, Galagan, JE. (2006). Combo: a whole genome comparative browser. Bioinformatics 22, 1782-1783.

Wang Z, Xiao X, Van Nostrand E, Burge CB. (2006). General and specific functions of exonic splicing silencers in splicing control. Mol. Cell 23, 61-70.

Yahyanejad M, Burge CB, Kardar M. (2006). Untangling influences of hydrophobicity on protein sequences and structures. Proteins 62, 1101-6.

Holste D, Huo G, Tung V, Burge CB. (2006). HOLLYWOOD: a comparative relational database of alternative splicing. Nucl. Acids Res. 34, D56-62.

2005

Farh KK, Grimson A, Jan C, Lewis BP, Johnston WK, Lim LP, Burge CB, Bartel DP (2005). The widespread impact of mammalian microRNAs on mRNA repression and evolution. Science 310, 1817-1821.

Goranov AI, Katz L, Breier AM, Burge CB, Grossman AD. (2005). A transcriptional response to replication status mediated by the conserved bacterial replication protein DnaA. PNAS 102, 12932-12937. PDF (Open Access).

Han K, Yeo G, An P, Burge CB, Grabowski PJ. (2005). A combinatorial code for splicing silencing: UAGG and GGGG motifs. PLoS Biol. 3, e158. PDF (Open Access).

Lewis BP, Burge CB, Bartel DP. (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20.

Ohler U, Shomron, N, Burge, CB. (2005). Recognition of unknown conserved alternatively spliced exons. PLoS Comp. Biol. 1, e15:0001-0010. PDF (Open Access).

Pfarr N, Prawitt D, Kirschfink M, Schroff C, Knuf M, Habermehl P, Mannhardt W, Zepp F, Fairbrother W, Loos M, Burge CB, Pohlenz J. (2005). Linking C5 deficiency to an exonic splicing enhancer mutation. J. Immunol. 174, 4172-4177.

Yeo G, Van Nostrand E, Holste D, Poggio T, Burge CB. (2005). Identification and analysis of alternative splicing events conserved in human and mouse. Proc. Natl. Acad. Sci. USA 102, 2850-2855. PDF (Open Access).

Padgett RA, Burge CB. (2005). Splice sites. In: Encyclopedia of Life Sciences. John Wiley & Sons, Ltd: Chichester http://www.els.net/

2004

Eng L, Coutinho G, Nahas S, Yeo G, Tanouye R, Babaei M, Dork T, Burge C, Gatti RA. (2004). Nonclassical splicing mutations in the coding and noncoding regions of the ATM gene: maximum entropy estimates of splice junction strengths. Hum. Mutat. 23, 67-76.

Fairbrother WG, Holste D, Burge CB, Sharp PA. (2004). Single nucleotide polymorphism-based validation of exonic splicing enhancers. PLoS Biol. 2(9), e268: 1-8. PDF at PLoS Biology web site.

Fairbrother, WG, Yeo G, Yeh R-F, Goldstein P, Mawson M, Sharp PA, Burge CB. (2004). RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons. Nucl. Acids Res. 32, W187-W190. PubMed Abstract and links to full text

Nielsen CB*, Friedman B*, Birren B, Burge CB, Galagan JE. (2004). Patterns of intron gain and loss in fungi. PLoS Biol. 2, e422. PDF (Open Access).

Ohler U, Yekta S, Lim LP, Bartel DP, Burge CB. (2004). Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. RNA 10, 1309-1322.

Seneff S, Wang C, Burge CB. (2004). Gene structure prediction using an orthologous gene of known exon-intron structure. Appl. Bioinformatics 3, 81-90.

Wang Z, Rolish ME, Yeo G, Tung V, Mawson M, Burge CB. (2004). Systematic identification and analysis of exonic splicing silencers. Cell 119, 831-845.

Yeo G*, Holste D*, Kreiman, G, Burge CB. (2004). Variation in alternative splicing across human tissues. Genome Biol. 5, R74. PDF (Open Access).

Yeo G, Hoon S, Venkatesh B, Burge CB. (2004). Variation in sequence and organization of splicing regulatory elements in vertebrate genes. Proc. Natl. Acad. Sci. USA 101, 15700-15705. PDF (Open Access).

Yeo G, Burge CB. (2004). Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals. J. Comp. Biol. 11, 377-394.

* These authors contributed equally.

2003

Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T. (2003). A uniform system for microRNA annotation. RNA 9, 277-279.

Arndt PF, Burge CB, Hwa T. (2003). DNA sequence evolution with neighbor-dependent mutation. J. Comp. Biol. 10, 313-322.

Katz L, Burge CB. (2003). Widespread selection for local RNA structure in coding regions of bacterial genes. Genome Res. 13, 2042-2051.

Lewis BP*, Shih I-h*, Jones-Rhoades MW, Bartel DP, Burge CB. (2003). Prediction of mammalian microRNA targets. Cell 115, 787-798.

Lim LP*, Glasner ME*, Yekta S*, Burge CB, Bartel DP. (2003). Vertebrate microRNA genes. Science 299, 1540.

Lim LP*, Lau, NC*, Weinstein EG*, Abdelhakim A*, Yekta S, Rhoades MW, Burge CB, Bartel DP. (2003). The microRNAs of Caenorhabditis elegans. Genes & Dev. 17, 977-990.

Yeo G, Burge CB. (2003). Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals. in Proceedings of the 7th Annual International Conference on Computational Molecular Biology (RECOMB03), W. Miller et al., eds., pp. 322-331 (ACM Press, New York).

* These authors contributed equally.

2002

Arndt PF, Burge CB, Hwa T. (2002). DNA sequence evolution with neighbor-dependent mutation. in Proceedings of the 6th Annual International Conference on Computational Molecular Biology (RECOMB02), G. Meyer et al., eds., ACM Press, New York, pp. 32-38.

Crollius HR, Jaillon O, Bernot A, Pelletier E, Dasilva C, Bouneau L, Burge C, Yeh R-F, Quetier F, Saurin W, Weissenbach J. (2002). Genome-wide comparisons between human and tetraodon. Ernst Schering Res. Found Workshop 36, 11-29.

Fairbrother W*, Yeh R-F*, Sharp PA, Burge CB. (2002). Predictive identification of exonic splicing enhancers in human genes. Science 297, 1007-1013. PDF at Science web site.

Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, and Bartel DP. (2002). Prediction of plant microRNA targets. Cell 110, 513-520.

* These authors contributed equally.

 

2001

Burge, CB. (2001). Chipping away at the transcriptome. Nature Genet. 27, 4-6.

Das M*, Burge CB*, Park E., Colinas J, Pelletier J. (2001). Assessment of the total number of human transcription units. Genomics 77, 71-78.

International Human Genome Sequencing Consortium (2001). Initial sequencing and analysis of the human genome. Nature 409, 860-921.

Lim LP, Burge CB. (2001). A computational analysis of sequence features involved in recognition of short introns. Proc. Natl. Acad. Sci. USA 98, 11193­11198.

Yeh R-F, Lim LP, Burge CB. (2001) Computational inference of homologous gene structures in the human genome. Genome Res. 11, 803-816.

* These authors contributed equally


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